What is the difference between creatine and creatinine

Microsoft is encouraging users to upgrade to its more modern Edge browser for improved security and functionality. This site is intended for healthcare professionals. Sign in. This is good or bad? I saw a gentleman in the office — 50 years old, fanatical fitness buff and I mean buff who took several grams of creatine daily and was sent to me with serum creatinine of 2.

When the creatine was stopped, his creatinine want back down to 1. Conversion of creatine to creatinine is non-enzymatic, I suspect simply mass balance-driven. I would bet that most reported cases of "kidney damage" with creatine aren't kidney-related at all….

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Learn more about kidney disease and what you can do to stay healthy and prevent the progression of kidney disease here. Two simple tests for kidney disease. Skip to main content. You are here Home » A to Z » Creatinine.

What is creatinine? What is a normal level of creatinine? That depends on your age, race, gender, and body size. Can my healthcare provider know if my kidneys are working properly by looking at how much creatinine is in my blood? Creatinine is a chemical product formed by breaking down creatine phosphate in muscles.

The production of creatinine depends upon the muscle mass of a person, and it is released at a constant rate by the body. It is present in plasma and serum, and it is transported through the kidneys into the blood, filtered, and then excreted in the form of urine. The level of creatinine is higher in men than in women because men have more skeletal muscles than women. Concentrations of creatinine in the blood are used to calculate the GFR, i. GFR is used to measure the function of the kidney, and it is clinically important.

If there is malfunctioning in the kidneys, then the level of creatinine will increase in the blood. So creatinine clearance CrCl is used to measure the concentrations of creatinine in blood and urine.

Eating a lot of protein can increase creatine which in turn will increase the creatinine excretion. If there is a low level of creatinine in the body, then it can cause malnutrition, muscle atrophy , debility, sedentary lifestyle, and multiple sclerosis. Both Creatine and Creatinine are found in our blood in the body.